Roderick was born on August 24, 1981. Briffa is a product of the Birkirkara F.C. Youth Nursery. In 1998 Roderick made his debut in the Premier League with the Stripes.

In season 2001-2002 Roderick Briffa joined Pieta Hotspurs on loan. He returned back with the stripes in season 2002. He made a total of 105 appearances for the Stripes before joining Sliema Wanderers in summer 2007.

International midfielder Roderick Briffa joined Valletta F.C. in January 2009.